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IgM antibody

Product Code Applications Pack Size List Price Your Price Qty
STAR86
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 1 mg loader
List Price Your Price
loader

Goat anti Mouse IgM antibody recognizes murine IgM and is cross-adsorbed to reduce reactivity with other mouse heavy or light chains.

Target Species
Mouse
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to mouse IgM were raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide
Immunogen
Mouse IgM mu heavy chain.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 5ug/ml as coating antibody
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

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References for IgM antibody

  1. Yan, Y. et al. (2003) Pathogenesis of autoimmunity after xenogeneic thymus transplantation.
    J Immunol. 170 (12): 5936-46.
  2. Fish, J.E. et al. (2005) The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code.
    J Biol Chem. 280: 24824-38.
  3. Lehours, P. et al. (2009) Is there a link between the lipopolysaccharide of Helicobacter pylori gastric MALT lymphoma associated strains and lymphoma pathogenesis?
    PLoS One. 4: e7297.
  4. Skoglund, A. et al. (2012) A changing gastric environment leads to adaptation of lipopolysaccharide variants in Helicobacter pylori populations during colonization.
    PLoS One. 4: e5885.
  5. Schweighoffer, E. et al. (2013) The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.
    Immunity. 38: 475-88.
  6. Vanderstock, J.M. et al. (2018) Phagocytosis, bacterial killing, and cytokine activation of circulating blood neutrophils in horses with severe equine asthma and control horses.
    Am J Vet Res. 79 (4): 455-64.
  7. Joshi, D. et al. (2021) Novel ablative laser mediated transdermal immunization for microparticulate measles vaccine.
    Int J Pharm. 606: 120882.
  8. Tchen, J. et al. (2024) PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus.
    Nat Commun. 15 (1): 3389.
  9. View The Latest Product References

Chromatin Immunoprecipitation

Flow Cytometry

Western Blotting

RRID
AB_321863
UniProt
P01872
P01873
Entrez Gene
Ighm
Ighm
GO Terms
GO:0000187 activation of MAPK activity
GO:0005515 protein binding
GO:0002455 humoral immune response mediated by circulating immunoglobulin
GO:0003823 antigen binding
GO:0004888 transmembrane receptor activity
GO:0009897 external side of plasma membrane
GO:0019815 B cell receptor complex
GO:0019882 antigen processing and presentation
GO:0030890 positive regulation of B cell proliferation
GO:0042571 immunoglobulin complex, circulating
GO:0043410 positive regulation of MAPKKK cascade
GO:0045022 early endosome to late endosome transport
GO:0045807 positive regulation of endocytosis
GO:0048471 perinuclear region of cytoplasm
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050853 B cell receptor signaling pathway
GO:0016021 integral to membrane

STAR86

151881 160620 162995 168052

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