To help you with your experiments, we have developed a range of useful mini-reviews, educational summaries, and blogs.
You can access our antibody resources by clicking on the relevant sections.
Mini-review on B cell history, development and activation as well as B cells as therapeutic targets. B cells are an integral part of the adaptive immune response. They represent a distinct lineage, with separate and unique functions from T cells.
Overview of the T cell marker CD3, including genes, function and clinical applications for the CD3 protein complex.
This guide provides a snapshot of key information for the design and study of eight T helper subsets.
Mini-review on the various isoforms of CD45 including their structure and function. CD45 is a type I transmembrane consisting of two intracellular phosphatase domains, a transmembrane domain and an extracellular domain.
Mini-review on the complement system, each of its pathways and complement components involved. Includes a summary on C4d, a known marker of allograft rejection.
Mini-review on rat anti-mouse F4/80 antibody (CI:A3-1), providing a technical overview about F4/80 antigen and antibody.
Mini-review on human and mouse macrophage polarization, and an introduction into macrophage classification and function, including macrophage involvement in cancer.
This mini-review characterizes monocytes, providing an overview of their lineage, the classification of the various subsets of monocytes, their function and the role they play in diseases.
Mini-review about the natural killer (NK) cell family functions, receptors and cell development in mouse and human.
Mini-review discussing the role of Toll-like receptors (TLRs) in neuroinflammation, explaining the TLR pathway, and the role of TLRs in brain cells.
Discover the role played by T cell receptors (TCR) in cell-mediated immune defence. Initial descriptions of TCRs were made 30 years ago primarily through similarity with immunoglobulin DNA sequences.
The structure and regulation of mucosal homeostasis and how this relates to disease and potential immunotherapy.
Function and mechanism of immune checkpoints in immune regulation and cancer immunotherapy.
Mini-review about Toll-like receptors, detailing their role in innate immunity including their expression patterns.
Discover the mechanisms behind immunosurveillance, immunosuppression and cancer immunotherapy.
Mini-review on Innate lymphoid cells covering ILC development, characterization, function and role in disease and immunotherapy.
Learn about eukaryotic cell cycle progression and regulation, cell proliferation assessments, and key cell proliferation biomarkers.
Toll-like receptors (TLRs) are one of the key receptor families forming an initial line of defence against invading pathogens. They are pattern recognition receptors (PRRs) along with the mannose (CD206), NOD, and NALP receptors.
TREM-1 stands for triggering receptor expressed on myeloid cells 1. It belongs to the v-type immunoglobulin superfamily, and is considered to be an orphan immunoreceptor because its ligand has not yet been identified. The TREM-1 receptor is expressed on monocytes, macrophages, and neutrophils...
CD209, originally called DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin), is a 45 kDa type-2 transmembrane protein that belongs to the group II C-type lectins.
Dectin-1 is a 33 kDa type-2 transmembrane protein that is a member of the Group V non-classical C-type lectins. It is also known as the beta-glucan receptor (ßGR) and the C-type lectin domain family 7, member A (CLEC7A).
This blog discusses a recent study by Bohn et al. (2018) that highlights a mechanism that melanoma utilizes to subvert the immune response....
Krishnamoorthy et al. (2018) have identified enucleated neutrophil cell bodies, known as ‘ghosts’, as driving Th17 cell inflammation in severe asthma....
Th2A cells are a recently identified subset of T helper cells type 2 (Th2). This blog looks at the role of Th2A cells in allergy....
Baranska et al. (2018) identify macrophage dynamics as being key to tattoos lasting. This blog examines why tattoos are so difficult to remove....
This blog describes studies demonstrating the beneficial role of commensal bacteria in treating microbial infections and antibiotic resistance....
Learn how a new tool from Bio-Rad simplifies knowing what markers to use to identify certain immune cell types....
This blog post describes the mechanisms by which macrophages induce insulin resistance in the obese state....
This post describes the role of monocytes in heart disease and whether monocyte infiltration into the heart exacerbates disease or aids in its repair....
This blog post discusses recent pre-clinical studies that suggest monocytes could be applied in a related manner to the treatment of diseases. ...
The new finding of trained immunity challenges the basic tenets of immunology, blurring the line that separates innate and adaptive immunity....
Have a group of researchers really found the key to a cure to the currently incurable Dengue virus? Find out here......